Searchable abstracts of presentations at key conferences in endocrinology

ea0026p722 | Diabetes (epidemiology, pathophysiology) | ECE2011

Impact of INSR His1085 and IRS1 Gly972Arg genetic variability on dyslipidaemia in patients with metabolic syndrome and type 2 diabetes

Katalinic D , Nikolac N , Zjacic-Rotkvic V , Solter M , Topic E , Vrkljan M , Plestina S

Introduction: The metabolic syndrome is increasingly recognized as a powerful predictor of patient risk for developing cardiovascular and cerebrovascular complications. It is viewed as the phenotypic confluence of atherogenic dyslipidaemia, hypertension, central obesity and insulin resistance (with or without type 2 diabetes) resulting from dysregulated gene expression and lifestyle behaviours.Aim: Because insulin resistance is a core defect in type 2 di...